The reason for this, and you can learn moreīy reading my article on irritable bowel syndrome, is that although there are no visible lesions (hard lesions), many times there are functional lesions (soft lesions) in the nervous system, In these conditions, there are no visible lesions in the nervous system, yet we see a similar type of motility dysfunction. Functional GI disorders include conditions such as irritable bowel syndrome (IBS), colonic inertia, and Now, with this in mind, we now will look at what are called ‘functional GI disorders’. This disruption causes decreased motility, which can cause constipation. When these neural pathways or neuronsĪre damaged, signals sent between the brain and the gut become disrupted. When we talk about constipation as it relates to damage to the brain or spinal cord or diseases that affect the brain or spinal cord, such as Parkinson’s disease, stroke, multiple sclerosis,Įtc., the reason that these conditions can cause constipation is that the brain regions and neural pathways that control intestinal motility become damaged. Let’s take a look at some of the conditions listed above, so you can getĪ better understanding of what I mean by this. Matter through the colon and out of the body (constipation) is often due to decreased signaling along the brain-gut axis. Now, in the absence of some type of obstruction (such as a tumor or diverticula), or another explanation for constipation (such as medications or diet low in fiber), the inability to move fecal Ultimately leaves the body due to peristaltic movements of intestinal wall musculature initiated by the brain. 15 – 20 Fecal matter passes through the colon and The GI tract is controlled by the brain through neurological pathways that make up what is called the brain-gut axis and the gut-brain axis.
The Brain-Gut/Gut-Brain Axes and Constipation Okay, now that we have a general idea of the causes constipation, let’s take a more detailed look at this symptom. Anismus (a type of dystonia where the anal sphincter fails to relax) 14.Hypothyroidism and hormonal disorders 2 3.Colon cancer or tumors in the GI tract 2.Colonic Motility Disorders 3 (including colonic inertia 3 8 and Pelvic floor dysfunction 3 9).Disorders affecting the brain and spine, including Parkinson’s disease 2 3.Spinal cord or brain injury (including stroke) 2 3 8.Numerous medications and vitamin supplements including 2 3:Īnd numerous medical conditions, including (but not limited to):.Inadequate or decreased fiber in the diet 2 3.The most common causes of constipation are: The most prevalent causes of constipation, then I’ll tell you more about what I mean by decreased electrochemical neural signaling to the intestines. There are numerous causes to constipation, but most of the causes are due to decreased electrochemical neural signaling to the intestines, and more specifically, the colon.
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